Showing posts with label microbes. Show all posts
Showing posts with label microbes. Show all posts

Saturday, October 4, 2008

Aromatherapy – More Than Just Good Smell

Aromatherapy is a form of alternative healing that makes use of volatile plant oils, referred to as essential oils, and other aromatic compounds obtained from plants for the overall physical and psychological well-being of a person.

The history of aromatherapy dates back to more than 3500 years before Christ’s birth, to a time when the use of aromatics was recorded for the first ever instance in human history. The truth is that the history of aromatherapy is deeply linked with the progress of aromatic medicine, which in its initial stages was typically combined with religion, mysticism and magic.

In India, around 2000 BC, various writings mention the role of ‘perfumers’ and ‘incense sellers’. The word ‘aromatherapy’ was used for the first time in the 1920s by French chemist Rene-Maurice-Gattefosse, who dedicated his life to researching on the discipline of aromatherapy.

The theory to explain the healing effects of aromatherapy offers two mechanisms- the influence of aroma on the brain, on the limbic system through the olfactory system in particular, and the direct pharmacological effects these essential oils have on the body.

Though the efficacy of aromatherapy as a form of healing has not yet been proven, but some clinical studies have shown encouraging results.

An overview of the materials frequently employed in aromatherapy is given below:

•Essential oils: These are fragrant oils extracted from plants mainly through steam distillation (e.g. eucalyptus oil).

•Absolutes: These are also fragrant oils, but extracted from flowers or delicate plant tissues through solvent extraction (e.g. rose absolute).

•Phytoncides: These are volatile organic compounds obtained from plants that destroy microbes.

•Hydrosols: These are aqueous by-products of distillation (e.g. rosewater). Many herbs are used to make herbal distillates. They have culinary, medicinal as well as skin care uses.

•Infusions: They are aqueous extracts of various plant materials (e.g. infusion of chamomile)

•Carrier oils: These are oily plant based triacylglycerides used to dilute essential oils for use on the skin (e.g. sweet almond oil) so as to avoid irritation.

Like any other form of healing, aromatherapy too has its uses and benefits. It doesn’t just smell good but provides immense relaxation and stress relief. It boosts the immune, respiratory and circulatory systems which help in mood enhancement and overall well being.

Essential oils, which form the heart of aromatherapy, pose some potential concerns as well. Because they are highly concentrated, they can cause skin irritation if used directly. They could also raise some health issues for pregnant and lactating women.

But on the whole, one can say that the positive effects of aromatherapy far outnumber the negative ones. It is an alternative to medicine that entails systematic use of organic essences in holistic treatments for enhancing general vitality and ensuring prevention of disease.

http://www.themedguru.com/




Tuesday, August 19, 2008

Skin Care: Scar-free Healing Shown With Gene Suppression

New research from the University of Bristol shows that by suppressing one of the genes that normally switches on in wound cells, wounds can heal faster and reduce scarring. This has major implications not just for wound victims but also for people who suffer organ tissue damage through illness or abdominal surgery.

When skin is damaged a blood clot forms and cells underneath the wound start to repair the damage, leading to scarring. Scarring is a natural part of tissue repair and is most obvious where skin has healed after a cut or burn. It ranges from trivial (a grazed knee) to chronic (diabetic leg ulcers) and is not limited to the skin. All tissues scar as they repair; for example, alcohol-induced liver damage leads to fibrosis and liver failure, and after most abdominal surgeries scars can often lead to major complications.

Tissue damage triggers an inflammatory response by white cells to protect skin from infection by killing microbes. The same white cells guide the production of layers of collagen. These layers of collagen help the wound heal but they stand out from the surrounding skin and result in scarring. Research by Professor Paul Martin and colleagues at the University of Bristol shows that osteopontin (OPN) is one of the genes that triggers scarring and that applying a gel, which suppresses OPN to the wound, can accelerate healing and reduces scarring. It does this in part by increasing the regeneration of blood vessels around the wound and speeding up tissue reconstruction.

Speaking of the discovery, Professor Martin said: ‘White blood cells (macrophages), and the chemical signals (PDGF) delivered to the wound cells, and osteopontin itself are now all clear targets for developing medicines to improve healing of skin wounds and other organs where fibrotic tissue repair can be debilitating. We hope that it won’t be too long before such therapies are available in the clinic. Indeed, the technique for suppressing OPN to reduce scarring is currently being licensed and patented by a Biotech company specializing in wound-healing therapies.’

Earlier research by Professor Martin’s lab and others has shown that embryos of many species, including humans, heal wounds without leaving a scar. Now it looks like the same may be true for adults.

The findings will be published by the Journal of Experimental Medicine on 26 January in a paper entitled ‘Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring’. The paper is currently available online

http://www.sciencedaily.com/



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